| Server IP : 192.169.170.185 / Your IP : 216.73.216.97 Web Server : Apache System : Linux p3plmcpnl495852.prod.phx3.secureserver.net 4.18.0-553.52.1.lve.el8.x86_64 #1 SMP Wed May 21 15:31:29 UTC 2025 x86_64 User : akhilnew ( 1712764) PHP Version : 5.6.40 Disable Function : NONE MySQL : ON | cURL : ON | WGET : ON | Perl : ON | Python : ON | Sudo : OFF | Pkexec : OFF Directory : /home/akhilnew/public_html/thepharmajournal/vol3Issue10/ |
Upload File : |
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Strict//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-strict.dtd">
<html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en">
<head>
<meta name="Description" content="This study investigated in vivo antioxidant effect of quercetin in normal rat brain and in vitro effect of quercetin on cerebral sodium pump" />
<meta name="keywords" content="Quercetin, Ouabain, Routes of Administration, Antioxidant Effect, Cerebral Sodium Pump Inhibitor."/>
<title>Quercetin elevates antioxidant status and modulates ouabain-sensitive transmembrane sodium pump in rat brain</title>
<meta http-equiv="Content-Type" content="text/html; charset=iso-8859-1" />
<meta name="Distribution" content="Global" />
<meta name="Author" content="Erwin Aligam - ealigam@gmail.com" />
<meta name="Robots" content="index,follow" />
<link rel="stylesheet" href="images/FreshMedia.css" type="text/css" />
<style type="text/css">
<!--
.style1 {
font-size: 16px;
color: #FF0033;
}
.style4 {color: #FF0033}
.style5 {color: #000000}
.style3 {
color: #FF0000;
font-weight: bold;
}
.style6 {
color: #000000;
font-weight: bold;
}
.style10 {color: #FF0033; font-weight: bold; }
.style11 {font-family: "Times New Roman", Times, serif}
.style12 { font-size: 14px;
font-weight: bold;
}
.style13 {color: #FF0000}
-->
</style>
</head>
<script type="text/javascript">
var _gaq = _gaq || [];
_gaq.push(['_setAccount', 'UA-29701333-1']);
_gaq.push(['_trackPageview']);
(function() {
var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true;
ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js';
var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s);
})();
</script>
<body>
<!-- wrap starts here -->
<div id="wrap-out"><div id="wrap">
<!--header -->
<div id="header">
<h1 id="logo-text"><a href="http://www.thepharmajournal.com/" title="">The Pharma Innovation</a></h1>
<div id="nav">
<ul>
<li id="current"><a href="../index.html">Home</a></li>
<li><a href="../Editorial_Board.html">Editorial Board</a></li>
<li><a href="../archives.html">archives</a></li>
<li><a href="../instructions.html">instruction to authors</a></li>
<li></li>
<li><a href="../contact_us.html">contact us</a></li>
</ul>
</div>
<!--header ends-->
</div>
<!-- content-wrap starts -->
<div id="content-wrap">
<div id="main">
<h2 align="center" class="style6">Volume <span class="style11">3</span>, Issue <span class="style11">10</span></h2>
<p> </p>
<h6 align="center" class="style1"><strong>Quercetin elevates antioxidant status and modulates ouabain-sensitive transmembrane sodium pump in rat brain</strong></h6>
<h6 align="center" class="style1"><br />
</h6>
<p><span class="style10">Author: </span><span class="style5">Akinwumi Ogundajo, Joshua Imoru, Ige Kade, Theophilus Olawoye</span></p>
<p><span class="style10">Abstract: </span><span class="style5">This study investigated <em>in vivo</em> antioxidant effect of quercetin in normal rat brain and <em>in vitro</em> effect of quercetin on cerebral sodium pump. Brain antioxidant factors (phenol, flavonoid, TBARS, Vitamin C and GSH) of normal male Wistar rats were quantified spectrophotometrically, while <em>in vitro</em> effect of quercetin on cerebral sodium pump was investigated through enzyme assay by measuring the of phosphate (Pi). The results showed that <em>in vivo</em> administration of quercetin significantly (P<0.001) increased brain’s phenol and flavonoid contents and significantly (P<0.001) decreased TBARS irrespective of the routes of administration. Intraperitoneal route caused significant (P<0.001) antioxidant effect compared to oral route of administration. <em>In vitro</em> investigation showed quercetin (IC50 73.68 µm) like ouabain (IC50 12.21 µm) as a moderate inhibitor of cerebral sodium pump. Its inhibitory effect can be modulated when the incubating medium was altered. Quercetin elevates cerebral antioxidant factors and modulates cerebral sodium pump in normal rats. </span> </p>
<p> </p>
<p><span class="style10">Download Full Article:</span> <strong><a href="Issue_dec_2014/12.1.pdf">Click Here </a></strong></p>
<p> </p>
<h3><strong>Support Us</strong></h3>
<p class="style5">If you are interested in supporting our work and would like to contribute, you are
welcome to mail me at jpbr.anil@gmail.com or at info@thepharmajournal.com it will
be a great help and will surely be appreciated.</p>
<p class="style5"><a href="http://www.phytojournal.com/" target="_blank"><img src="images/headerphoto70.jpg" alt="Advertisement" width="532" height="146" /></a></p>
<p> </p>
</div>
<!-- sidebar starts -->
<div id="sidebar">
<h3 class="style4"><a href="http://www.phytojournal.com/" target="_blank"><span class="style12"><span class="style13">Call Us: (Helpline)<br />
Toll Free (India):</span> <span class="style5">1800-1234-070<br />
<span class="style13">India:</span> +91-9711224068<br />
<span class="style13">Rest of World:</span> +91-9810852116</span></span></a></h3>
<h3 class="style4">ISSN 2277-7596</h3>
<h3><a href="http://www.phytojournal.com/" target="_blank"><img src="images/cognosy.jpg" alt="Pharmacognosy Journal" width="206" height="146" longdesc="http://www.phytojournal.com/" /></a></h3>
<h3>Journal code(s)</h3>
<p class="style3">ISSN Number: <span class="style5">2277-7695</span><br />
CODEN Code: <span class="style5">PIHNBQ</span><br />
ZDB-Number: <span class="style5">2663038-2 </span><br />
IC Journal ID: <span class="style5">7725</span></p>
<h3>Sidebar Menu</h3>
<ul class="sidemenu">
<li><a href="http://www.thepharmajournal.com/">Home</a></li>
<li><a href="http://www.thepharmajournal.com/Editorial_Board.html">Editorial Board</a></li>
<li><a href="http://www.thepharmajournal.com/archives.html">Archives</a></li>
<li><a href="http://www.thepharmajournal.com/instructions.html">Instructions to Author</a></li>
<li><a href="http://www.thepharmajournal.com/indexing.html" title="Web Templates">Indexing and Abstracting</a></li>
<li><a href="http://thepharmajournal.com/publication_fee.html">Publication Fee</a></li>
<li><a href="http://www.thepharmajournal.com/contact_us.html" title="Web Templates">Contact Us</a></li>
</ul>
<h3>Wise Words</h3>
<p class="style5">"You will not be punished for your anger, you will be punished by your anger." by <span class="style4">Buddha</span>.
<!-- sidebar ends -->
</p>
<p class="style5"> </p>
</div>
<!-- content-wrap ends-->
</div>
<!-- footer starts here -->
<div id="footer-wrap">
<div id="footer-content">
<div class="col float-left space-sep">
<h3>Important Links</h3>
<p><a href="http://www.thepharmajournal.com/important_links.html" title="The Pharma Innovation">Important Links</a></p>
<p><a href="http://www.thepharmajournal.com/Payment_Options.html">Payment Options</a></p>
<p><a href="http://www.thepharmajournal.com/archives.html">Archives</a></p>
</div>
<div class="col float-left">
<h3> </h3>
<p><a href="http://www.thepharmajournal.com/Advertise_with_us.html" title="The Pharma Innovation">Advertise With Us</a></p>
<p><a href="http://www.thepharmajournal.com/certificate.html">Certificate</a></p>
<p><a href="http://www.thepharmajournal.com/Disclaimer.html" title="The Pharma Innovation">Disclaimer</a><a href="http://www.thepharmajournal.com/" title="The Pharma Innovation"></a></p>
<p> </p>
<p align="center"><span class="style5">© copyright 2012 <strong>The Pharma Innovation</strong></span></p>
</div>
<div class="col2 float-right">
<h3> </h3>
<p><a href="http://www.thepharmajournal.com/indexing.html" title="The Pharma Innovation">Abstracting and Indexing</a></p>
<p><a href="http://www.thepharmajournal.com/sitemap.html" title="The Pharma Innovation">Site Map</a></p>
<p><a href="http://www.thepharmajournal.com/contact_us.html" title="The Pharma Innovation">Contact us</a></p>
</div>
</div>
</div>
<div class="clearer"></div>
<!-- footer ends here -->
<!-- wrap ends here -->
</div></div>
</body>
</html>